You can animate just about anything..however in the case of Legomation..its usually a LEGO character or vehicle etc. What you will need as a basic however is a LEGO board to stick your characters onto in order to keep them stable when you are moving their limbs. You know the board / base you stick your houses and Lego onto..thats the one!

(by NikolaOtrov)

The one limitation you will notice once you have done a few Legomations is that you will not be able to animate their mouth movements. However don't worry, their are some tips and tricks you can use to minimise this.